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Index > Protein center > NR1H4(Gene name) > Bovine
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  • NR1H4 (Gene name),
  • Bile acid receptor (Protein name ),  NR1H4_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NR1H4;
    Protein name:
    Bile acid receptor;
    Alternative:
    Farnesol receptor HRR-1;Farnesoid X-activated receptor;Nuclear receptor subfamily 1 group H member 4;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Heterodimer of NR1H4 and RXR. Interacts with CARM1 and SMARD1. After activation by agonist binding, interacts with a coactivator, NCOA1 or NCOA2.
    Function:
    Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    482
    Sequence:
    50:
    MVMQFQELEN | PVQISPCHSH | TSSGFDMEVM | SMKPAKGVLT | EQVAGPLGQN | 
    100:
    LEVEPYSQYN | NVQFPQVQPQ | ISSSSYYSNV | GFYPQQPEEW | YSPGIYELRR | 
    150:
    MPAETLYQGE | TEVVEIPITK | KARLGASAGR | IKGDELCVVC | GDRASGYHYN | 
    200:
    ALTCEGCKGF | FRRSITKNAV | YKCKNGGNCV | MDMYMRRKCQ | ECRLRKCKEM | 
    250:
    GMLAECLLTE | IQCKSKRLRK | NVKQHADQAI | HEDSEGRDLR | QVTSTTKSCR | 
    300:
    EKTELTPDQQ | NLLHYIMDSY | SKQRMPQEIT | NKFLKEEFSA | EENFIILTEM | 
    350:
    ATSHVQVLVE | FTKKLPGFQT | LDHEDQIALL | KGSAVEAMFL | RSAEIFSKKL | 
    400:
    PAGHTDLLEE | RIRKSGISDE | YITPMFSFYK | SVAELKMTQE | EYALLTAIVI | 
    450:
    LSPDRQYIKD | REAVEKLQEP | LLDVLQKLCK | IHQPENPQHF | ACLLGRLTEL | 
    482:
    RTFNHHHADM | LMSWRVNDHK | FTPLLCEIWD | VQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Bile acid receptor
    Cat.:
    E2042h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Bile acid receptor
    Cat.:
    E2042r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Bile acid receptor
    Cat.:
    E2042m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Bile acid receptor
    Cat.:
    E2042b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Bile acid receptor
    Cat.:
    U2042b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Bile acid receptor
    Cat.:
    U2042r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Bile acid receptor
    Cat.:
    U2042m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Bile acid receptor
    Cat.:
    U2042h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Bile acid receptor
    Polyclonal Antibody for Bovine Bile acid receptor
    Cat.:
    P2042Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Bile acid receptor
    Cat.:
    P2042Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Bile acid receptor
    Cat.:
    P2042Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Bile acid receptor
    Monoclonal Antibody for Bovine Bile acid receptor
    Monoclonal Antibody for Bovine Bile acid receptor
    Monoclonal Antibody for Bovine Bile acid receptor
    Protein for Bovine Bile acid receptor
    Protein for Bovine Bile acid receptor
    Protein for Bovine Bile acid receptor
    Protein for Bovine Bile acid receptor

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      tissue: Ileum.
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